منابع مشابه
Dispersed Aortic Smooth Muscle Cells
Studies on hormone induced contraction of vascular smooth muscle strips in vitro have yielded a large body of pharmacological and biochemical data (1). Unfortunately, vascular strips possess inherent limitations for answering certain questions concerning sites of hormone binding on their constituent smooth muscle cells. Diffusion barriers in the tissue may hinder the use of macromolecular recep...
متن کاملIntegrin Receptors on Aortic Smooth Muscle Cells
Extracellular matrix receptors on vascular smooth muscle cells help in anchoring the cells during contraction and in promoting cellular migration after vessel injury. We found that rat aortic smooth muscle cells attach to surfaces coated with fibronectin, laminin, and collagen types I and IV. Cell attachment to these substrates appears to be mediated by members of the f1 integrin family of extr...
متن کاملCultured Bovine Aortic Endothelial and Smooth Muscle Cells
Endothelial cell (EC) injury and the response of EC and smooth muscle cells (SMCs) to injury contribute to the pathophysiology in patients with vascular disease and atherosclerosis. Since platelets have been suggested to play an important role in modulating vascular injury, the present study was undertaken to examine the influence and mechanism of action of individual platelet factors on bovine...
متن کاملSomite-derived cells replace ventral aortic hemangioblasts and provide aortic smooth muscle cells of the trunk.
We have previously shown that endothelial cells of the aortic floor give rise to hematopoietic cells, revealing the existence of an aortic hemangioblast. It has been proposed that the restriction of hematopoiesis to the aortic floor is based on the existence of two different and complementary endothelial lineages that form the vessel: one originating from the somite would contribute to the roof...
متن کاملFunctional recapitulation of smooth muscle cells via induced pluripotent stem cells from human aortic smooth muscle cells.
RATIONALE Generation of induced pluripotent stem (iPS) cells has been intensively studied by a variety of reprogramming methods, but the molecular and functional properties of the cells differentiated from iPS cells have not been well characterized. OBJECTIVE To address this issue, we generated iPS cells from human aortic vascular smooth muscle cells (HASMCs) using lentiviral transduction of ...
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ژورنال
عنوان ژورنال: The Journal of Japan Atherosclerosis Society
سال: 1988
ISSN: 0386-2682,2185-8284
DOI: 10.5551/jat1973.16.5_623